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The effect of haematiopoietic cell transplantation (HCT) on hyposalivation, xerostomia and caries progression

Marjolein Saartje Bulthuis • Boek • paperback

  • Samenvatting
    Free download at https://doi.org/10.54195/9789493296749

    Haematopoietic cell transplantation is an established treatment option for (malignant) blood diseases like leukaemia. This treatment, which is preceded by chemotherapy and/or radiation therapy, is known to cause oral side effects. The mean salivary flow rate decreased shortly after transplantation, was lowered 3 months thereafter, and recovered to baseline levels after 12 months. Many patients experienced mouth dryness: complaints increased shortly after treatment and, even though complaints decreased in the long term, 73% of the patients still experienced mouth dryness 5 years after the transplantation. A shortage of saliva produced under resting conditions (unstimulated saliva), was likely to cause mouth dryness complaints, but also patients with a normal salivary flow rate experienced complaints. If the salivary flow rate could not be stimulated sufficiently by chewing, the risk of cavities increased.
  • Productinformatie
    Binding : Paperback
    Distributievorm : Boek (print, druk)
    Formaat : 170mm x 240mm
    Aantal pagina's : 189
    Uitgeverij : Radboud University Press
    ISBN : 9789493296749
    Datum publicatie : 11-2024
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